Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Intracardiac Thrombosis in Sickle Cell Disease.

(2016) Intracardiac Thrombosis in Sickle Cell Disease. Iranian Journal of Medical Sciences.

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In patients with sickle cell disease, thrombotic microangiopathy is a rare complication. Also in sickle cell disease, intracardiac thrombus formation without structural heart diseases or atrial arrhythmias is a rare phenomenon. We herein describe a 22-year-old woman, who was a known case of sickle cell-βthalassemia, had a history of recent missed abortion, and was admitted with a vaso-occlusive crisis. The patient had manifestations of microangiopathic hemolytic anemia, including laboratory evidence of hemolytic anemia, thrombocytopenia, respiratory distress, fever, jaundice, and abnormal liver function and coagulation tests, accompanied by clot formation on the Eustachian valve of the inferior vena cava in the right atrium and also a long and worm-like thrombus in the right ventricle. Therapeutic plasma exchange improved her clinical condition, and her intracardiac thrombus was completely resolved after 1 week. Echocardiography, as a simple and inexpensive imaging modality, had a significant role in the diagnosis and follow-up of this patient.

Item Type: Article
Keywords: Plasmapheresis; Sickle cell anemia; Thrombotic microangiopathy
Subjects: cardiovascular
Divisions: Research Vice-Chancellor Department > Cardiovascular Research Center
Depositing User: مرکز تحقیقات قلب و عروق

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