Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Comparison of Immunohistochemical Coloring, Hematoxyline and Eosin Staining for Detecting of Lymphatic Metastasis in patients with Breast Cancer and Negative Lymph Node Involvement

(2019) Comparison of Immunohistochemical Coloring, Hematoxyline and Eosin Staining for Detecting of Lymphatic Metastasis in patients with Breast Cancer and Negative Lymph Node Involvement. PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES.

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Abstract

Background: The patients with breast cancer are examined for detecting lymph node involvement and metastasis by Hematoxyline and Eosin staining which is routinely used and may have fase negative. Aim: To compare immunohistochemical detection of lymph node metastasis with Hematoxyline and Eosin staining with EMA and Cytokeratin (CK) antigens in patients with breast cancer and Negative lymph node involvement.. Methods: In this observational retrospective cross-sectional study, 64 consecutive patients with breast cancer who had negative H and E results were enrolled and the EMA and CK results were determined and compared with H and E. Results: The EMA and CK results were negative in all patients showing 100% congruence with H & E results for lymph node metastasis. Conclusion: there is high congruence rate for detection of lymph node metastasis with Hematoxyline & Eosin staining and EMA and CK.

Item Type: Article
Keywords: Hematoxyline & Eosin; EMA; CK; lymphatic metastasis MICROMETASTASES; MANAGEMENT
Subjects: QW Microbiology and Immunology > QW 1-300 Microbiology
QZ Pathology > QZ 200-380 Neoplasms
WP Gynecology and Obstetrics > WP 800-910 Breast
endocrine
Depositing User: هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/6607

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