Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

The association between microcytic anemias and spirometric parameters.

(2019) The association between microcytic anemias and spirometric parameters. Adv Respir Med.

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Official URL: https://www.ncbi.nlm.nih.gov/pubmed/30830953

Abstract

Background Microcytic anemias are a group of anemias with smaller than normal red blood cells. Iron deficiency anemia and thalassemia are some of the major causes. The aim of this study was to compare the pulmonary function of the subjects with microcytic anemias to the normal population. Methods This was a cross-sectional study in Bandar Abbas, Iran conducted on the patients attending yearly occupational health checkups. Complete blood cell count and a standard spirogram were attained from each consenting participant and the occupational history of exposure to dust, fumes, solvents, and noxious gases was obtained. Results At last, 2210 subjects were included in the analysis of which there were 154 cases of iron deficiency anemia and 181 cases of thalassemias. There was significant association between having microcytic anemias and forced vital capacity (mostly in thalassemia cases) and also peak expiratory flow and mid-range flow (mostly in iron deficiency anemia). The last two also significantly increased with each unit increase of hemoglobin levels. Conclusion It can be concluded that the reduction in hemoglobin levels and having microcytic anemia (both thalassemia and iron deficiency anemia) may reduce some spirometric parameters. Even though these changes are small, adjusting for these reduced values can help prevent overestimation of lung disorders mostly in borderline cases.

Item Type: Article
Keywords: Microcytic anemia; iron deficiency anemia; lung function; spirometry; thalassemia
Subjects: WF Respiratory System > WF 140-900 Diseases of the Respiratory System
Depositing User: هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/6330

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