Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

The Association Between the Transforming Growth Factor Beta-1 -509C > T Gene Polymorphism and Primary Open Angle Glaucoma in North Eastern Iran

(2019) The Association Between the Transforming Growth Factor Beta-1 -509C > T Gene Polymorphism and Primary Open Angle Glaucoma in North Eastern Iran. Advances in Human Biology.

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Official URL: http://www.aihbonline.com/article.asp?issn=2321-85...

Abstract

Background: Brain tumours (BTs) constitute approximately 88% of all central nervous system tumours. The present study aimed to determine the age-standardised rate (ASR) of BTs in Iran. Methods: A comprehensive search was conducted on all studies of BTs incidence using Medline/PubMed, Scopus, Embase, Google Scholar and Web of Sciences as international databases and Scientific Information Database, MagIran, IranMedex and IranDoc as Iranian databases until April 2018. This systematic review was done based on the preferred reporting items for systematic reviews and meta-analyses. Results: The primary search yielded 312 relevant studies. A total of 17 studies were included after more detailed retrieval. The results of the random-effect model were demonstrated the ASR of BTs was 4.16 (95% confidence interval [CI], 3.20–5.12) for males and 3.40 (95% CI, 2.67–4.13) for females. Conclusion: The incidence of BTs is lower in Iran compared to other parts of the world. The incidence of nervous system cancers is increasing base on region, geographical, and economic conditions in Iran. Hence, training programmes can be considered to reduce the risk factors, complications of nervous system cancers and early diagnosis of nervous tumors.

Item Type: Article
Keywords: Brain tumours, incidence, Iran, systematic review
Subjects: QZ Pathology > QZ 200-380 Neoplasms
WA Public Health > WA 900-950 Statistics. Surveys
WL Nervous System > WL 200-405 Central Nervous System. Disorders. Therapeutics
Depositing User: هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/6248

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