Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Effect of tranexamic acid on postpartum vaginal hemorrhage in Sharieti Hospital of Bandar Abbas in 2014- 2015

(2018) Effect of tranexamic acid on postpartum vaginal hemorrhage in Sharieti Hospital of Bandar Abbas in 2014- 2015. JOURNAL OF RESEARCH IN MEDICAL AND DENTAL SCIENCE.

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Abstract

bstract As a midwifery emergency, post-partum hemorrhage (PPH) might occur once a vaginal delivery or C-section is done. The prevalence of the hemorrhage has been estimated to range between 1 and 5 percent of deliveries. The present clinical trial was conducted as a randomized and controlled double-blind study in 2014-15 on 240 pregnant visitors of the natural delivery ward of Shariati university hospital in Bandar Abbas. The intervention group received 1 gram of venal tranexamic acid in 200 ml of normal saline while the control group received a placebo (distilled water) in 200 ml of normal saline injected within the second phase of the childbirth in 10 minutes. Patients' information was recorded including the severity of hemorrhage, pre- and post-partum hemoglobin level as well as the clinical symptoms. The data were later analyzed via SPSS. The severity of hemorrhage was 313.9 +/- 46.8 in the intervention group and 729.3 +/- 199.6 in the control group which showed to be statistically significant (p<.001). Moreover, hemoglobin showed to be reduced in the intervention group for .1 +/-.16 and 1.72 +/-.11 in the control group which was statistically significant (p<.001). The present findings revealed that prescribed tranexamic acid can significantly cut down on blood loss and reduced hemoglobin in pregnant women.

Persian Abstract

Alavi, Azin)[ 1 ] ; Atiqpour, F (Atiqpour, Farzaneh)[ 2 ] ; Zare, S (Zare, Shahram)[ 3 ] ; Nasiri, Z (Nasiri, Zinat)[ 2 ]

Item Type: Article
Keywords: CESAREAN-SECTION; DOUBLE-BLIND; BLOOD-LOSS; DELIVERY; EXPRESSION; TRIAL Tranexamic Acid; Delivery; Obstetric; Hemorrhage
Subjects: WQ Obstetrics > WQ 500-505 Postpartum Period
Divisions: Research Vice-Chancellor Department > Fertility and Infertility Research Center
Depositing User: هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/5893

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