Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Research project #5413

(1394) بررسی مقاومت آنتی بیوتیکی وشیوع β-لاکتامازهای طیف گسترده ( ESBL ) تیپ های TEM و CTX-M واینتگرون کلاس یک در ایزوله های بالینی E.coli و K.pneumoniae جمع آوری شده از بیمارستان های شهید محمدی و خلیج فارس بندرعباس در سال 1394. completed.

[img] Text
گزارش نهایی طرح دکتر کرمستجی.doc
Restricted to Registered users only

Download (92kB)

Persian Abstract

ESBL phenotype was detected in 49 (26.3%) E. coli and 19 (32.8%) K. pneumoniae isolates. BlaVEB gene in 32(17.2%) E. coli and 5(8.6%) K. pneumoniae isolates. BlaPER gene in 4 (2.1%) E. coli and 0 (0%) K. pneumoniae isolates. Bla CTX-M gene in 113 (60.7%) E. coli and 34(58.6%) K. pneumoniae isolates. BlaTEM gene in 106 (57%) E. coli and 25 (43.1%) K. pneumoniae isolates. One hundred and nine (58.6%) of E. coli and 33(56.9%) of K. pneumoniae were carrying Class 1 integron and 18 (9.7%) of E. coli and 3 (5.2%) of K. pneumoniae were carrying Class 2 integron. Class 3 integron was not detected

Title

Assasement of antibiogram and Prevalence of TEM/ CTX-M Extended Spectrum β- Lactamases ( ESBL ) and class I integron in E.coli and K.pneumoniae Isolates from Shahid Mohammadi and Khalije Fars hospitals in Bandar-abbas in 2015

Abstract

Introduction: Multi-drug resistant Escherichia coli and Klebsiella pneumoniae with various resistance determinants are a major concern in hospital and community acquired infections around the world. Objective: To describe the presence of bla CTX-M,bla TEM,bla PER,bla VEB, and integrons class 1,2,3 and extended spectrum β lactamase (ESBL) phenotype in E. coli and K. pneumoniae isolates from inpatients and outpatients. Methods: One hundred and eighty six E. coli and fifty-eight K. pneumoniae were collected. Antimicrobial susceptibility test was performed by disk diffusion method. PCR assay was performed for blaTEM, bla CTX-M, bla PER and blaVEB and class 1,2,3 integrase genes. Statistical analysis was performed by chi-squared test. Results: ESBL phenotype was detected in 49 (26.3%) E. coli and 19 (32.8%) K. pneumoniae isolates. BlaVEB gene in 32(17.2%) E. coli and 5(8.6%) K. pneumoniae isolates. BlaPER gene in 4 (2.1%) E. coli and 0 (0%) K. pneumoniae isolates. Bla CTX-M gene in 113 (60.7%) E. coli and 34(58.6%) K. pneumoniae isolates. BlaTEM gene in 106 (57%) E. coli and 25 (43.1%) K. pneumoniae isolates. One hundred and nine (58.6%) of E. coli and 33(56.9%) of K. pneumoniae were carrying Class 1 integron and 18 (9.7%) of E. coli and 3 (5.2%) of K. pneumoniae were carrying Class 2 integron. Class 3 integron was not detected

Item Type: Research project
Subjects: QV Pharmacology > QV 350-370 Anti-Bacterial Agents. Tissue Extracts
QW Microbiology and Immunology > QW 1-300 Microbiology
Divisions: Research Vice-Chancellor Department > Infectious and Tropical Diseases Research Center
Depositing User: مركز تحقيقات بيماريهاي عفوني
URI: http://eprints.hums.ac.ir/id/eprint/5413

Actions (login required)

View Item View Item