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Hormozgan University of Medical Sciences

Acute kidney injury in intensive care unit: incidence, risk factors and mortality rate

(2011) Acute kidney injury in intensive care unit: incidence, risk factors and mortality rate. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.

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Abstract

Acute kidney injury (AKI) is a risk factor for increased mortality in critically ill patients. To assess the incidence, risk factors and outcome of patients who develop AKI in the intensive care units (ICUs), we retrospectively studied 235 patients admitted to the ICU of Shahid Mohamadi Hospital, Hormozgan, Iran, and compared those who developed AKI and those who did not. There were 31.1 of patients who developed AKI during ICU admission. There was a significant difference in the mean age, serum sodium (Na), potassium (K), urea, blood urea nitrogen (BUN) and creatinine (Cr) levels and also platelets, on admission, between patients with and without AKI. Acute physiology and chronic health evaluation (APACHE) II score on admission was significantly higher in AKI patients and Glasgow coma scale (GCS) was significantly lower. The mortality of AKI patients (72.6) was significantly higher than non-AKI patients (25.91). The number of underlying diseases and GCS and APACHE II score on admission were significantly different between the expired and survived patients. We conclude that age, first serum K level and APACHE II score on admission time were powerful independent predictors of developing AKI in ICU patients. The GCS on admission and the presence of two or more underlying diseases accurately predict the mortality in AKI positive ICU patients.

Item Type: Article
Additional Information: cited By 15
Keywords: creatinine; potassium; sodium; urea, acute kidney failure; adolescent; adult; age; aged; article; blood; child; female; hospitalization; human; incidence; intensive care unit; Iran; length of stay; male; middle aged; mortality; preschool child; retrospective study; risk factor; statistical model; statistics; thrombocyte; urea nitrogen blood level, Acute Kidney Injury; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Blood Platelets; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Female; Humans; Incidence; Intensive Care Units; Iran; Length of Stay; Logistic Models; Male; Middle Aged; Potassium; Retrospective Studies; Risk Factors; Severity of Illness Index; Sodium; Urea; Young Adult
Subjects: WJ Urogenital System > WJ 300-378 Kidney
Depositing User: مهندس هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/5393

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