Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Paraoxonase enzyme activity and dyslipidemia in chronic kidney disease patients

(2012) Paraoxonase enzyme activity and dyslipidemia in chronic kidney disease patients. Journal of Nephropathology.

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Abstract

Recent studies have focused on decrease activity of paraoxonase (PON) in chronic kidney disease (CKD) patients. Paraoxonase (PON) enzyme is altered in many diseases and is related to lipid abnormalities and antioxidant activities. Patients with CKD often have lipid abnormalities. Lipid abnormalities in CKD patients increase the risk of cardiovascular diseases in CKD patients. In CKD patients, PON activity and its mechanism have developed a new idea for treatment options to reduce the risk of cardiovascular disease. This review article is focused on the role of PON in dyslipidemia in the CKD patients. © 2014 by Journal of Nephropathology (JNP).

Item Type: Article
Additional Information: cited By 35
Keywords: Chronic renal failure; Dyslipidemia; Paraoxonase
Subjects: WJ Urogenital System > WJ 300-378 Kidney
Depositing User: مهندس هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/5291

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