Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

The impact of human papillomavirus (HPV) types 6, 11 in women with genital warts

(2012) The impact of human papillomavirus (HPV) types 6, 11 in women with genital warts. Archives of Gynecology and Obstetrics.

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Abstract

Objective: Human papillomaviruses (HPV) are etiologically associated with the development of virtually all genital warts. HPV-6 and HPV-11 are the most commonly detected HPV genotypes, but at least 20 other HPV genotypes have occasionally been found in genital wart tissue specimens. Study design: The aim of this study was to determine from 100 genital wart tissue specimens collected from female patients using multiplex gap-PCR technique the prevalence of various genital HPV among women with HPV genital warts in south of Iran. 100 genital wart tissue specimens were tested for the presence of HPV PG5/PG6 and also for HPV type using polymerase chain reaction (PCR). Results: Based on the collected data, 73 (73 ) samples were detected positive for HPV DNA and 23 (23 ) samples out of 100 samples were detected negative for HPV DNA. 49 (49 ) and 67 (67 ) of patients were detected positive for HPV type 6 and 11, respectively. There was a significant association between marital status and HPV genotype 6 (OR = 0.51, 95 CI = 0.37-0.70, P = 0.01). Nevertheless, no significant association was found between marriage and HPV genotype 11 (OR = 0.85, 95 CI = 0.58-1, 24, P = 0.7). Similarly, this result was demonstrated, in combined marriage and HPV-general (OR = 0.80, 95 CI = 0.62-0.05, P = 0.4). Conclusion: Concerning the prevalence of HPV in our study, determination of genital HPV prevalence and multiple infections among the normal population of women of Hormozgan Province is recommended. © 2012 Springer-Verlag.

Item Type: Article
Additional Information: cited By 4
Keywords: DNA fragment; virus DNA, adult; article; condyloma acuminatum; disease association; DNA extraction; female; female genital tract parameters; genotype; human; Human papillomavirus type 11; Human papillomavirus type 6; human tissue; Iran; major clinical study; marriage; multiplex polymerase chain reaction; passive smoking; prevalence; risk assessment; risk factor; virus detection, Adult; Condylomata Acuminata; Confidence Intervals; DNA, Viral; Female; Genotype; Human papillomavirus 11; Human papillomavirus 6; Humans; Iran; Marital Status; Odds Ratio; Prevalence; Young Adult
Subjects: WC Communicable Diseases > WC 500-590 Virus Diseases
WP Gynecology and Obstetrics > WP 650-660 Therapy
Depositing User: مهندس هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/5262

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