Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Severe anemia and hydrops in a neonate with parvovirus B19 infection: A case report

(2013) Severe anemia and hydrops in a neonate with parvovirus B19 infection: A case report. Tehran Univ Med J.

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Background: Anemia at the time of birth may cause some problem like asphyxia, heart failure shock or even death in a neonate. Different etiologies can be considered for this problem. Parvovirus B19, as a viral organism, can cause hydrops fetalis and neonatal anemia and consequent complications. We present here a case of newborn infant with severe anemia who had human parvovirus B19 infection. Case Presentation: A male newborn with gestational age of 36 week was born from a mother with poor prenatal care and history of contact with domestic animal. The neonate was very pale with Apgar score 2 at 1 min and received resuscitation, mechanical ventilation and repeated blood transfusion The hemoglobin level was significantly low. Analysis was made based on the clinical presentations. According to the case history, physical and laboratory findings, neonatal severe anemia induced by parvovirus B19 infection was suggested and Laboratory work up documented his infection with parovirus B19. Conclusion: Parvovirus B19 (B19 virus) is the smallest single strand linear DNA virus in animal viruses, which is the only strain of parvovirus that is pathogenic in humans. Human parvovirus B19 may cross the placenta and result in fetal infection, morbidity and death. Parvovirus is an uncommon cause of neonatal anemia and hydrops fetalis so this etiology must be considered in differential diagnosis of anemia at birth.

Item Type: Article
Keywords: Anemia Hydrops fetalis Neonate Parvovirus B19
Subjects: QY Clinical Laboratory Pathology > QY 400-490 Hematologic Tests. Blood Chemical Analysis
WC Communicable Diseases > WC 500-590 Virus Diseases
WS Pediatrics > WS 405-460 By Age Groups
Depositing User: مهندس هدی فهیم پور

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