Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Inhibitory activity of green tea (Camellia sinensis) extract on some clinically isolated cariogenic and periodontopathic bacteria

(2013) Inhibitory activity of green tea (Camellia sinensis) extract on some clinically isolated cariogenic and periodontopathic bacteria. Medical Principles and Practice.

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Abstract

Objective: To determine the in vitro inhibitory activity of green tea extract on some clinically isolated cariogenic and periodontopathic bacteria. Materials and Methods: Twenty strains of each of Streptococcusmutans, Aggregatibacteractinomycetemcomitans, Porphyromonasgingivalis, and Prevotellaintermedia were isolated from carious teeth and periodontal pockets of patients with dental caries and periodontal diseases. Green tea extract was prepared by aqueous extraction method and diluted from 50 to 1.56 mg/ml. Standard techniques of agar disk diffusion and broth microdilution assays were applied for qualitative and quantitative determinations of antibacterial activity of green tea extract on each isolates. Results: All clinical isolates of S. mutans (100) were sensitive to green tea extract at concentrations 6.25, 12.5, 25, and 50 mg/ml producing inhibition zones ranging from 10 to 38 mm. All periodontopathic isolates (A. actinomycetemcomitans, n = 20, P. intermedia, n = 20, and P. gingivalis, n = 20) (100) tested were sensitive to 12.5, 25, and 50 mg/ml of this extract. The minimal inhibitory concentration of green tea extract for S. mutans was 3.28 ± 0.7 mg/ml and for A. actinomycetemcomitans 6.25, for P. gingivalis and P. intermedia 12.5 mg/ml. Conclusions: Our findings showed that green tea extract exhibited strong antibacterial activity on S. mutans,A. actinomycetemcomitans,P. gingivalis and P. intermedia and therefore may be used in mouthwashes or dentifrices for prevention of dental caries and periodontal diseases. Copyright © 2013 S. Karger AG, Basel.

Item Type: Article
Additional Information: cited By 22
Keywords: green tea extract; agar; amikacin; cariogenic agent; green tea extract; phosphate buffered saline; vancomycin, Aggregatibacter actinomycetemcomitans; antibacterial activity; article; broth dilution; controlled study; dental caries; disk diffusion; human; in vitro study; minimum inhibitory concentration; nonhuman; periodontal disease; periodontal pocket; Porphyromonas gingivalis; Prevotella intermedia; Streptococcus mutans; tea; Article; assay; bacterium isolation; Camellia sinensis; dental caries; periodontal disease; periodontal pocket; periodontopathic bacteria, Aggregatibacter actinomycetemcomitans; Camellia sinensis; Dental Caries; Humans; Microbial Sensitivity Tests; Periodontal Diseases; Plant Extracts; Porphyromonas gingivalis; Prevotella intermedia; Streptococcus mutans
Subjects: QV Pharmacology > QV 350-370 Anti-Bacterial Agents. Tissue Extracts
WC Communicable Diseases > WC 195-425 Infection. Bacterial Infections
Depositing User: مهندس هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/5135

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