Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Effectiveness of hysteroscopic repair of uterine lesions in reproductive outcome

(2014) Effectiveness of hysteroscopic repair of uterine lesions in reproductive outcome. International Journal of Fertility and Sterility.

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Abstract

Background: Small intrauterine lesions such as septum, adhesion, polyp, and submucous myoma may be of greater significance in causing implantation failure, poor reproductive performance and abnormal uterine bleeding. We studied effectiveness of therapeutic intervention through operative hysteroscopy in improvement of pregnancy outcome and cessation of abnormal uterine bleeding (AUB) in women with pregnancy and fertility problems. Materials and Methods: This prospective cohort study was performed between 2003- 2009 on 65 patients with primary or secondary infertility, recurrent abortion and structural uterine lesions reported in sonography or hysterosalpingography. After hysteroscopic metroplasty, myomectomy, adhesiolysis and polypectomy under laparoscopic guide, we evaluated reproductive outcome, early and late complications, one year after surgery. Results: Among all patients with recurrent abortion, 6 patients (75) complete their pregnancy successfully. Our results showed that pregnancy rate after metroplasty was 58. Reproductive outcome was poor after myomectomy and adhesiolysis. Abnormal uterine bleeding was improved in 62 of patients. Conclusion: Structural uterine lesions has been assumed to cause infertility, while several studies have shown very poor reproductive performance with high miscarriage and low term delivery rates when malformation is not treated. We show improvement in conceptional outcome and in patient's chief complaints after hysteroscopy surgery of these anomalies.

Item Type: Article
Additional Information: cited By 4
Keywords: estrogen; medroxyprogesterone acetate, abortion; adhesiolysis; adult; article; echography; endometrium polyp; female; female infertility; fever; human; hysterectomy; hysterorrhaphy; hysteroscopy; lesions and defects; major clinical study; myomectomy; ovariectomy; ovary abscess; parity; polypectomy; pregnancy outcome; prospective study; recurrent abortion; uterine lesion; uterus bleeding; uterus myoma; uterus surgery
Subjects: WQ Obstetrics > WQ 215-270 Pregnancy Complications
Depositing User: مهندس هدی فهیم پور
URI: http://eprints.hums.ac.ir/id/eprint/4990

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