Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Insecticide susceptibility of Anopheles stephensi to DDT and current insecticides in an elimination area in Iran

(2016) Insecticide susceptibility of Anopheles stephensi to DDT and current insecticides in an elimination area in Iran. Parasites and Vectors.


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Background: Iran has recently initiated a malaria elimination program with emphasis on vector control strategies which are heavily reliant on indoor residual spraying and long-lasting insecticidal nets. Insecticide resistance seriously threatens the efficacy of vector control strategies. This study was conducted to determine the insecticide susceptibility of Anopheles stephensi to DDT and current insecticides in Jask county as an active malaria focus in southeastern Iran. Methods: In this study, the anopheline larvae were collected from different aquatic habitats in Jask county and transported to insectarium, fed with sugar and then 3-day-old adults were used for susceptibility tests. WHO insecticide susceptibility tests were performed with DDT (4 ), malathion (5 ), lambda-cyhalothrin (0.05 ), deltamethrin (0.05 ) and permethrin (0.75 ). Results: The field strain of An. stephensi was found resistant to DDT and lambda-cyhalothrin. The LT50 values for DDT and lambda-cyhalothrin in this species were 130.25, and 37.71 min, respectively. Moreover, An. stephensi was completely susceptible to malathion and permethrin and tolerant to deltamethrin. Conclusion: The present study results confirm the resistance of the major malaria vector, An. stephensi, to DDT and lambda-cyhalothrin, and tolerance to deltamethrin, which could gradually increase and spread into other malaria endemic areas. Thus, there is a need for regular monitoring of insecticide resistance in order to select suitable insecticides for vector control interventions towards malaria elimination. © 2016 The Author(s).

Item Type: Article
Additional Information: cited By 2
Keywords: chlorphenotane; cyhalothrin; deltamethrin; insecticide; malathion; permethrin; sugar; nitrile; pyrethroid, adult; Anopheles stephensi; arthropod larva; Article; controlled study; exposure; female; insecticide resistance; Iran; mortality rate; nonhuman; parasite clearance; rearing; animal; Anopheles; larva; malaria; mosquito control; mosquito vector; procedures, Animals; Anopheles; DDT; Insecticide Resistance; Insecticides; Iran; Larva; Malaria; Malathion; Mosquito Control; Mosquito Vectors; Nitriles; Permethrin; Pyrethrins
Subjects: WD Disorders of Systemic, Metabolic or Environmental Origin, etc. > WD 300-380 Immunologic and Collagen Diseases. Hypersensitivity
Divisions: Education Vice-Chancellor Department > Faculty of Medicine > Department of Basic Science > Immunology Department
Depositing User: مهندس هدی فهیم پور

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