Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Strong ion gap in brain dead patients and its role in predicting outcome in liver transplantation

(1393) Strong ion gap in brain dead patients and its role in predicting outcome in liver transplantation. آنستزیولوژی و مراقبتهای ویژه ایران.

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Abstract

Background: Liver transplantation is the treatment of choice in end stage liver disease. Marginal graft is a criteria for selecting appropriate liver in many centers. Many studies indicated that SIG is a good predictor for outcome. Our primary objective was to find a correlation between SIG and graft function. Secondary objective was comparison between SIG and marginal graft criteria. Material and methods: This study was performed in 61 liver recipients. All recipients were selected for transplantation by marginal graft criteria. Strong ion was measured and according to ionized portion SIG was calculated. According to cut of point of SIG=10 and marginal graft criteria, patients were divided into two groups and then compared with each other. Results: This study was conducted on 61 liver recipients. 39 (63.9%) of them developed with transplantation complication. Only 3(4.9%) presented with PNF and 1 (1.6%) presented with DNF. Mean SIG was 18.41 1.71. 49.2% of livers was marginal. 68% of donors had SIG>10 and 32% had SIG 10. No difference was seen in these two groups according to liver transplantation complication. (Pvalue: 0.286) In group SIG>10 mean AST was 297730 and mean ALT was 292 438 and in group SIG10 mean AST and ALT was 350566 and 383440 respectively. This difference is clinically significant. No difference was seen in marginal and non-marginal graft according to liver transplantation complication. (Pvalue:0.245) Conclusion: SIG in donor is not an appropriate predictor for liver transplantation outcome.

Item Type: Article
Keywords: SIG, Marginal graft, Liver transplantation.
Subjects: anesthesia
Divisions: Research Vice-Chancellor Department > Anaesthesiology, Critical Care and Pain Management Research Center
Depositing User: مركز تحقيقات بیهوشی و مراقبتهای ویژه
URI: http://eprints.hums.ac.ir/id/eprint/3166

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