Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Research project #3059

(2014) مطالعه اثرمادهGeinstein جدا شده از سویا در کنترل هیپرمتیلاسیون پروموتور و نیز میزان بیان ژن TMS-I در سرطان معده. completed.

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Title

The impact of soy-derived Geinstein in control of promotor hypermethylation and expression of TMS-I gene in Stomach cancer

Abstract

Dietary and nutritional factors have been reported to have gene expression and genome modulating effects that may pertain to the development or prevention of certain cancers. For example, some epidemiological studies suggest that a diet rich in fruits and vegetables, including soy, may be associated with a decreased risk of breast and other cancers [1, 2, 3]. In some Asian populations consuming traditional high phytoestrogen diets, epidemiological data correlate diet with reduced incidence of hormone-responsive cancers, and Asian women usually exhibit higher urinary and plasma phytoestrogen levels than women in Western populations [4]. Cancer development may also be prevented in part by the induction of apoptosis, thereby eliminating potentially damaged cells [5] or by interactions with signal transduction pathways in tumor cells as recently shown for lycopene [6].

Item Type: Research project
Subjects: gastrointestinal and hepatic
molecular Genetics
genetic
pharmacology
Divisions: Research Vice-Chancellor Department > Molecular Medicine Research Center
Depositing User: مرکز تحقیقات پزشکی مولکولی
URI: http://eprints.hums.ac.ir/id/eprint/3059

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