Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Assessment of Anti- Inflammatory effect of sea urchin Echinometra mathaei From the Persian Gulf

(2016) Assessment of Anti- Inflammatory effect of sea urchin Echinometra mathaei From the Persian Gulf. ISMJ.

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Abstract

Background: sea urchins belonging to phylum echinoderms of marine invertebrates them found to possess excellent. Inflammation can be considered a set of complex processes that many body systems including the immune and nervous system are involved. The aim of the present research was undertaken to study the anti- inflammatory activity of different extracts, coelomic fluid and pigments shells and spines of sea urchin of Echinodermata mathaei. Material and method: Isolation of different tissues extracts (spine, shell, gonad and aristotol lantern) sea urchin by three solvents (n- hexan, ethyl acetate, methanol). Isolation coelomic fluid by buffered mode and pigments shell and spine by HCl of sea urchin evaluation antioxidant (DPPH radical scavenging) and anti- inflammatory activity investigated through inhibition albumin serum denaturation. Resuts: According to the results of the study, the spine- methanoli and coelomic fluid (CF) had the highest activity in the DPPH radical scavenging and aristotol lantern- ethyl acetate and pigment shell highest activity in the anti- inflammatory methods. Significant differences were observed at P<0.05. Conclusion: The result of this research indicated that sea urchin of E.mathaei due to the high antioxidant activity, have anti- inflammatory activities too.

Item Type: Article
Keywords: Anti- inflammatory activity, sea urchin, Echinodermata mathaei ,Persian Gulf
Subjects: biochemistry
Divisions: Research Vice-Chancellor Department > Molecular Medicine Research Center
Depositing User: مرکز تحقیقات پزشکی مولکولی
URI: http://eprints.hums.ac.ir/id/eprint/2112

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