Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Double First Cousin Marriage and Genetic Disorders in South of IRAN

(2015) Double First Cousin Marriage and Genetic Disorders in South of IRAN. American Journal of Life Science Researches.

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Abstract

Abstract: Marriage between persons biologically related as second cousins are known as consanguineous. Double first cousins arise when siblings of one family reproduce with siblings of another family. A consanguineous couple especially double cousin couple is at increased risk for both autosomal recessive disorders and several congenital malformations. This study is designed in order to illustrate the prevalence of first double cousin marriage and its outcomes in Hormozgan province in south of IRAN. This is a cross-sectional study. Participants are 68 couples who came to medical genetic counseling center because of first double cousin marriage between 2003 to 2013. In 10 years from 2003-2013 genetic counseling was done for 4800 couples. 2856 couples (59.5%) had consanguineous marriage. 68 couples were double first cousin (1.4%). Double first cousin marriage is high risk for offspring to have genetic disorders. Counseling and giving knowledge and information to couples could encourage them to avoid high risk marriages like double first cousin.

Item Type: Article
Keywords: Double First Cousin, Marriage, Genetic Disorders
Subjects: genetic
Divisions: Research Vice-Chancellor Department > Molecular Medicine Research Center
Depositing User: مرکز تحقیقات پزشکی مولکولی
URI: http://eprints.hums.ac.ir/id/eprint/1133

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