Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

The Impact of Genetic Counseling on Prevention of Mental Retardation

(2014) The Impact of Genetic Counseling on Prevention of Mental Retardation. Journal of Life Science and Biomedicine.


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ABSTRACT: Mental retardation has high prevalence in south of Iran because of consanguineous marriages. As no definite cure is available for mental retarded individuals, prevention is the best way .This study was designed to evaluate the impact of genetic counselling on prevention of mental retardation. This case control study was carried out between 2010-2013 and 120 women with mental retarded children were participated. All of them had another pregnancy after their mental retarded child. of those, 60 women had pregnancy after genetic counselling (case group) and 60 women had pregnancy without doing genetic counselling (control group).The study data was analysed using SPSS19.Genetic counselling before pregnancy was protective factor for having mental retarded child. (Odds Ratio 4.261, 95% confidence interval 1.312-13.834). Results indicated that 71.7% of parents in case group and 55% in control group had consanguineous marriages. Screening tests in pregnancy were done in 78.3% of mothers in case group and 21.7% in control group. Down syndrome was the most common cause of mental retardation in both groups. Genetic counselling is effective in prevention of mental retardation. It's suggested that health authorities inform and educate mothers about genetic counselling before pregnancy, specifically women with mental retarded children.

Item Type: Article
Keywords: Mental Retardation, Genetic Counselling, Pregnancy
Subjects: genetic
Divisions: Research Vice-Chancellor Department > Molecular Medicine Research Center
Depositing User: مرکز تحقیقات پزشکی مولکولی

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