Repository of Research and Investigative Information

Repository of Research and Investigative Information

Hormozgan University of Medical Sciences

Research project #1047

(2013) بررسی مولکولی هاپلوتیپ های کلاستر ژن زنجیره بتا در ارتباط با موتاسیونهای رایج مسئول تالاسمی ماژور در استان هرمزگان. completed.

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Persian Abstract

A limited number of haplotypes are found in each population, and each haplotype is usually associated with one specific type of thalassemia. When mutation analysis fails, haplotype analysis is useful in identifying a β-thal chromosome, with an accuracy of about 90% if the family is informative.Despite the few studies on types of β-thalassemia mutations in southwestern Iran, RFLP haplotypes of β-thalassemia chromosomes have not been yet determined.

Title

Molecular Analysis of β-Globin Gene Cluster Haplotypes in related to spectrum of common mutations of major β-thalassemia in Hormozgan Province

Abstract

A limited number of haplotypes are found in each population, and each haplotype is usually associated with one specific type of thalassemia. When mutation analysis fails, haplotype analysis is useful in identifying a β-thal chromosome, with an accuracy of about 90% if the family is informative.Despite the few studies on types of β-thalassemia mutations in southwestern Iran, RFLP haplotypes of β-thalassemia chromosomes have not been yet determined.

Item Type: Research project
Subjects: genetic
Divisions: Research Vice-Chancellor Department > Molecular Medicine Research Center
Depositing User: مرکز تحقیقات پزشکی مولکولی
URI: http://eprints.hums.ac.ir/id/eprint/1047

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